What is synthesis chemical reaction in chemistry?
The term synthesis was first used by the chemist Herman Kolbe. In chemistry, chemical synthesis is the synthesis of useful chemicals by artificial means.
These reactions consist of few steps to produce product from reactants. These chemical reactions are known as synthesis chemical reaction.
In other words, the chemical reactions through which one more reactants are combined to produce essential compounds, that is, the chemical reactions those are relating to synthetic synthesis, is called synthesis chemical reaction.
In chemical synthesis, one or more reagents or reactants are added under certain conditions to form a productive substance.
For example, a laboratory synthesis of paracetamol may consist of three separate synthetic steps.
The desired product is made through synthesis chemical reaction. There are many techniques in chemical synthesis. Each chemical synthesis is multistep synthesis.
A large number of organic as well as inorganic compounds are synthesized by using synthesis chemical reaction.
Synthesis Chemical Reaction Examples
In chemistry, there are two types of chemical synthesis such as organic chemical synthesis and inorganic chemical synthesis.
Synthesis chemical reaction in organic chemistry
The spread of organic chemical synthesis is far greater and more important than inorganic synthesis.
Because of this, a lot of organic compounds are synthesized through synthesis chemical reaction. Organic synthesis is related to the synthesis of organic compounds.
If it starts with a product isolated from a plant or animal and then progresses to new compounds, synthesis is described as a semi-synthetic process.
Many organic compounds are synthesized by synthesis chemical reaction.
A few of well known and important synthesis chemical reaction for organic synthesis are listed below.
- Synthesis of paracetamol from nitrobenzene and phenol
- Synthetic synthesis of aspirin from phenol
- Gabriel phthalimide synthesis for primary amine
- Haworth synthesis of naphthalene
- Pschorr synthesis of phenanthrene
- Paal Knorr synthesis of pyrrole derivatives
- Fischer’s indole synthesis of indole
- Friedlander’s or Skraup synthesis of quinoline
- Synthesis of anti malarial drugs, tranquillizer’s drugs, anti biotic etc
Besides these, synthesis of sulfur drugs such as sulfanilamide, sulfadiazine, sulfa guanidine, sulfathiazole etc are also synthesized by synthesis chemical reaction. Chemical synthesis of some organic compound is shown below.
Friedlander’s synthesis of quinoline
When o-amino benzaldehyde is condensed with acetaldehyde in aqueous NaOH, then the synthesis product is quinoline. Acids are also effective catalysts for this synthesis reaction.
Gabriel phthalimide synthesis for primary amine
In Gabriel phthalimide synthesis, phthalimide is reacts first with ethanolic KOH form potassium phthalimide.
This potassium phthalate is attached with alkyl halide followed by basic hydrolysis produce primary amine.
Synthesis chemical reaction in inorganic chemistry
Inorganic chemical synthesis is applied to prepare inorganic compounds with significant non-organic content.
For example, preparation of the anticancer drug cis-Platin from tetrachloro- platinate (II).
- What is synthesis chemical reaction in chemistry?
- Synthesis chemical reaction examples
- Synthesis chemical reaction in organic chemistry
- Synthesis chemical reaction in inorganic chemistry
